{"id":527,"date":"2024-04-02T15:07:18","date_gmt":"2024-04-02T06:07:18","guid":{"rendered":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/?page_id=527"},"modified":"2024-04-02T15:07:18","modified_gmt":"2024-04-02T06:07:18","slug":"research","status":"publish","type":"page","link":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n<ol>\n<li>\u30e9\u30b8\u30ab\u30eb\u7a2e\u306b\u3088\u308b\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306e\u5909\u63db\u53cd\u5fdc<\/li>\n<\/ol>\n\n\n\n<p>\u6709\u6a5f\u30d5\u30c3\u7d20\u5316\u5408\u7269\u306f\u30d5\u30c3\u7d20\u539f\u5b50\u306e\u7279\u7570\u6027\u306b\u3088\u308a\u69d8\u3005\u306a\u5206\u91ce\u3067\u91cd\u5b9d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\uff0c\u6700\u8fd120\u5e74\u9593\u3067\u958b\u767a\u3055\u308c\u305f\u8fb2\u85ac\u306e\u7d045\u5272\u304c\u30d5\u30c3\u7d20\u5316\u5408\u7269\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059<sup>1<\/sup>\u3002\u305d\u306e\u305f\u3081\uff0c\u52b9\u7387\u7684\u306b\u30d5\u30c3\u7d20\u7f6e\u63db\u57fa\u3092\u6709\u6a5f\u5206\u5b50\u306b\u5c0e\u5165\u3059\u308b\u624b\u6cd5\u306e\u958b\u767a\u306f\u91cd\u8981\u306a\u7814\u7a76\u8ab2\u984c\u3067\u3042\u308a\u307e\u3059\u3002\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306f\u9077\u79fb\u91d1\u5c5e\u89e6\u5a92\u3084\u30a4\u30aa\u30f3\u53cd\u5fdc\u306a\u3069\uff0c\u4e8c\u96fb\u5b50\u5236\u5fa1\u306b\u3088\u308b\u624b\u6cd5\u304c\u4e00\u822c\u7684\u3067\u3042\u308a\u307e\u3057\u305f\u3002\u4e8c\u96fb\u5b50\u5236\u5fa1\u6cd5\u3067\u306f\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u90e8\u4f4d\u306f\u30cf\u30ed\u30b2\u30f3\u539f\u5b50\u306e\u4ee3\u308f\u308a\u3068\u3057\u3066\u50cd\u304d\uff0c\u91cd\u8981\u306a\u30d5\u30c3\u7d20\u5b98\u80fd\u57fa\u3092\u6700\u7d42\u751f\u6210\u7269\u3078\u3068\u5c0e\u5165\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3002\u3053\u308c\u306f3\u3064\u306e\u30d5\u30c3\u7d20\u539f\u5b50\u3068\u30b9\u30eb\u30db\u30f3\u306e\u96fb\u5b50\u6c42\u5f15\u6027\u306b\u3088\u308a\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u30a4\u30aa\u30f3\u304c\u975e\u5e38\u306b\u5b89\u5b9a\u3067\u3042\u308b\u3053\u3068\u306b\u8d77\u56e0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"556\" height=\"95\" src=\"\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-2.png\" alt=\"\" class=\"wp-image-157\" srcset=\"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-2.png 556w, https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-2-300x51.png 300w\" sizes=\"(max-width: 556px) 100vw, 556px\"><figcaption>\u5f93\u6765\u306e\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306e\u5229\u7528\u6cd5<\/figcaption><\/figure><\/div>\n\n\n\n<p>\u4e00\u65b9\uff0c\u79c1\u305f\u3061\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u3067\u306f\uff0c\u4e00\u96fb\u5b50\u5236\u5fa1\u306b\u3088\u308b\u624b\u6cd5\u3092\u7528\u3044\uff0c\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u30a4\u30aa\u30f3\u304c\u8131\u96e2\u3059\u308b\u306e\u3067\u306f\u306a\u304f\uff0c\u6709\u6a5f\u5408\u6210\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u6d3b\u6027\u7a2e\u3067\u3042\u308b\u30c8\u30ea\u30d5\u30eb\u30aa\u30ed\u30e1\u30c1\u30eb\u30e9\u30b8\u30ab\u30eb\u304c\u8131\u96e2\u3057\uff0c\u3053\u308c\u3092\u9375\u6d3b\u6027\u7a2e\u3068\u3057\u3066\u7528\u3044\u308b\u65b0\u898f\u5909\u63db\u53cd\u5fdc\u3092\u898b\u3044\u3060\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306b\u5bfe\u3057\u3066\u30c8\u30ea\u30a8\u30c1\u30eb\u30dc\u30e9\u30f3\uff08Et<sub>3<\/sub>B\uff09\u3084AIBN\u306a\u3069\u306e\u30e9\u30b8\u30ab\u30eb\u958b\u59cb\u5264\u3092\u4f5c\u7528\u3055\u305b\u308b\u3068\uff0c\u30c8\u30ea\u30d5\u30eb\u30aa\u30ed\u30e1\u30c1\u30eb\u30e9\u30b8\u30ab\u30eb\u306e\u751f\u6210\u3092\u7d4c\u3066\uff0c\u03b1-\u30c8\u30ea\u30d5\u30eb\u30aa\u30ed\u30e1\u30c1\u30eb\u30b1\u30c8\u30f3\u304c\u52b9\u7387\u3088\u304f\u5f97\u3089\u308c\u308b\u3053\u3068\u3092\u898b\u3044\u3060\u3057\u307e\u3057\u305f<sup>2,3<\/sup>\u3002\u672c\u624b\u6cd5\u3092\u7528\u3044\u308b\u3068\uff0c\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u4ee5\u5916\u306e\u30d3\u30cb\u30eb\u30da\u30eb\u30d5\u30eb\u30aa\u30ed\u30a2\u30eb\u30ab\u30f3\u30b9\u30eb\u30db\u30ca\u30fc\u30c8\u304b\u3089\u3082\u52b9\u7387\u3088\u304f\u30da\u30eb\u30d5\u30eb\u30aa\u30ed\u30a2\u30eb\u30ad\u30eb\u5316\u751f\u6210\u7269\u304c\u5f97\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-3.png\" alt=\"\" class=\"wp-image-158\" width=\"589\" height=\"287\" srcset=\"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-3.png 589w, https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-3-300x146.png 300w\" sizes=\"(max-width: 589px) 100vw, 589px\"><figcaption>\u672c\u7814\u7a76\u3067\u898b\u3044\u3060\u3057\u305f\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306e\u65b0\u3057\u3044\u5229\u7528\u6cd5<\/figcaption><\/figure><\/div>\n\n\n\n<p>\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306e\u7f6e\u63db\u57fa\u306e\u7a2e\u985e\u306b\u3088\u3063\u3066\u306f\uff0c\u5bb9\u6613\u306b\u52a0\u6c34\u5206\u89e3\u3092\u53d7\u3051\u308b\u305f\u3081\u7cbe\u88fd\u304c\u56f0\u96e3\u3068\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3053\u3067\uff0c\u30b1\u30c8\u30f3\u304a\u3088\u3073\u30a2\u30eb\u30ad\u30f3\u306e\u3044\u305a\u308c\u306e\u57fa\u8cea\u3092\u51fa\u767a\u57fa\u8cea\u3068\u3057\u3066\u7528\u3044\u3066\u3082\uff0cone-pot\u3067\u751f\u6210\u7269\u3092\u5f97\u3089\u308c\u308b\u3053\u3068\u3092\u898b\u3044\u3060\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"570\" height=\"172\" src=\"\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-4.png\" alt=\"\" class=\"wp-image-159\" srcset=\"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-4.png 570w, https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-content\/uploads\/2022\/07\/image-4-300x91.png 300w\" sizes=\"(max-width: 570px) 100vw, 570px\"><figcaption>One-pot\u53cd\u5fdc\uff08\u4e0d\u5b89\u5b9a\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u3082\u5229\u7528\u53ef\u80fd\uff09<\/figcaption><\/figure><\/div>\n\n\n\n<p>\u30c8\u30ea\u30d5\u30eb\u30aa\u30ed\u30e1\u30c1\u30eb\u57fa\u306e\u79fb\u52d5\u53cd\u5fdc\u306f\uff0c\u5206\u5b50\u5185\u53cd\u5fdc\u3068\u5206\u5b50\u9593\u53cd\u5fdc\u306e\u53cc\u65b9\u304c\u8003\u3048\u3089\u308c\u308b\u3002DFT\u8a08\u7b97\u304a\u3088\u3073\u30b9\u30af\u30e9\u30f3\u30d6\u30ea\u30f3\u30b0\u5b9f\u9a13\u304b\u3089\uff0c\u5206\u5b50\u9593\u53cd\u5fdc\u3067\u9032\u884c\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u3092\u5229\u7528\u3057\uff0c\u30a2\u30eb\u30b1\u30f3\u5171\u5b58\u4e0b\u3067\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306b\u5bfe\u3057\u3066\u30e9\u30b8\u30ab\u30eb\u958b\u59cb\u5264\u3092\u4f5c\u7528\u3055\u305b\u308b\u3068\uff0c\u30c8\u30ea\u30d5\u30eb\u30aa\u30ed\u30e1\u30c1\u30eb\u30e9\u30b8\u30ab\u30eb\u304c\u30a2\u30eb\u30b1\u30f3\u4ed8\u52a0\uff0c\u6b21\u3044\u3067\u30d3\u30cb\u30eb\u30c8\u30ea\u30d5\u30e9\u30fc\u30c8\u306b\u4ed8\u52a0\u3057\u30b1\u30c8\u30f3\u306e\u03b3\u4f4d\u306b\u30c8\u30ea\u30d5\u30eb\u30aa\u30ed\u30e1\u30c1\u30eb\u57fa\u3092\u6709\u3059\u308b\u5316\u5408\u7269\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f<sup>4<\/sup>\u3002<\/p>\n\n\n\n<p>\u53c2\u8003\u6587\u732e<\/p>\n\n\n\n<p>(1) Ogawa, Y.; Tokunaga, E.; Kobayashi, O.; Hirai, K.; Shibata, N. <em>iScience<\/em> <strong>2020<\/strong>, <em>23<\/em>, 101467.<\/p>\n\n\n\n<p>(2) Kawamoto, T.; Sasaki, R.; Kamimura, A. <em>Angew. Chem. Int. Ed.<\/em> <strong>2017<\/strong>, <em>56<\/em>, 1342\u20131345.<\/p>\n\n\n\n<p>(3) Kawamoto, T.; Noguchi, K.; Takata, R.; Sasaki, R.; Matsubara, H.; Kamimura, A. <em>Chem. Eur. J.<\/em> <strong>2021<\/strong>, <em>27<\/em>, 9529\u20139534.<\/p>\n\n\n\n<p>(4) Kawamoto, T.; Morioka, T.; Noguchi, K.; Curran, D. P.; Kamimura, A. <em>Org. Lett.<\/em> <strong>2021<\/strong>, <em>23<\/em>, 1825\u20131828.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6709\u6a5f\u30d5\u30c3\u7d20\u5316\u5408\u7269\u306f\u30d5\u30c3\u7d20\u539f\u5b50\u306e\u7279\u7570\u6027\u306b\u3088\u308a\u69d8\u3005\u306a\u5206\u91ce\u3067\u91cd\u5b9d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\uff0c\u6700\u8fd120\u5e74\u9593\u3067\u958b\u767a\u3055 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/pages\/527"}],"collection":[{"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/comments?post=527"}],"version-history":[{"count":1,"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/pages\/527\/revisions"}],"predecessor-version":[{"id":529,"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/pages\/527\/revisions\/529"}],"wp:attachment":[{"href":"https:\/\/ds0n.cc.yamaguchi-u.ac.jp\/~t-kwmt\/wp-json\/wp\/v2\/media?parent=527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}