研究業績


2024年

1. Tokunaga Y, Akiyama M, Nakano K, Konaka K, Taguchi A, Maeda T, Sato R, Kanda T, Nakamura Y,Yujiri T, Ohta Y. Diffuse Large B-cell Lymphoma Complicated with Anti-3-hydroxy-3-methylglutaryl-Coenzyme A Reductase Immune-mediated Necrotizing Myopathy: A Case Report.Intern Medin press.

2. Tokunaga Y, Nakamura Y, Ando T, Katsuki K, Sakai K, Fujioka Y, Nono S, Sasaki T, Yamamoto K, Akiyama M, Kawakami F, Kawakami T, Ishida F, Ohta Y,Yujiri T. T-cell large granular lymphocytic leukemia with STAT3 mutation successfully treated with cord blood transplantation.Intern Medin press.


 

2023年

1. Imai Y, Nagaya S, Araiso Y, Meguro-Horike M, Togashi T, Ohmori K, Makita Y, Sato E, Yujiri T, Nagamori Y, Horike S, Watanabe A, Morishita E. Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.Int J Hematol.117:523-529.2023 .

2. Tanaka N, Kunihiro Y, Kawano R,Yujiri T, Ueda K, Gondo T, Kobayashi T, Matsumoto T. Differential diagnosis of infectious diseases, drug-induced lung injury, and pulmonary infiltration due to underlying malignancy in patients with hematological malignancy using HRCT.Jpn J Rad iol. 41:27-37.2023.

3. 村田 竜也, 小原 健吾, 鹿嶋 聖, 平井 未来, 丸山 恭平, 池田 光泰, 福岡 達仁,湯尻 俊昭 SARS-CoV-2抗原定量検査の活用方法と有用性の検証 医学検査 72: 205–209.2023 

2022年

1. Kunihiro Y, Tanaka N, Kawano R,Yujiri T, Ueda K, Gondo T, Kobayashi T, Matsumoto T, Ito K. High-resolution CT findings of pulmonary infections in patients with hematologic malignancy: comparison between patients with or without hematopoietic stem cell transplantation.Jpn J Radiol. 40,791–799. 2022.

2. Kajimura Y, Nakamura Y, Hirano T, Tanaka Y, Yamamoto K, Tokunaga Y, Sasaki T, Oishi K,Yujiri T, Matsunaga K,Tanizawa Y. Significance of alveolar nitric oxide concentration in the airway of patients with organizing pneumonia after allogeneic hematopoietic stem cell transplantation. Ann Hematol. 101,1803–1813. 2022.

3. Okamoto Y, Hirano M, Morino K, Kajita MK, Nakaoka S, Tsuda M, Sugimoto KJ, Tamaki S, Hisatake J, Yokoyama H, Igarashi T, Shinagawa A, Sugawara T, Hara S, Fujikawa K, Shimizu S,Yujiri T, Wakita H, Nishiwaki K, Tojo A, Aihara K.Early dynamics of chronic myeloid leukemia on nilotinib predicts deep molecular response.NPJ Syst Biol Appl.8:39. 2022


2021年

1. Kajimura Y, Nakamura Y, Tanaka Y, Tanaka M, Yamamoto K, Matsuguma M, Tokunaga Y,Yujiri T, Tanizawa Y. Soluble Interleukin-2 Receptor Index Predicts Outcomes After Cord Blood Transplantation.Transplant Proceedings 53:379-385.2021

2. Tanaka N, Kunihiro Y, Kawano R,Yujiri T, Ueda K, Gondo T, Matsumoto T. Chest complications in immuno-compromisedpatients without acquired immunodeficiencysyndrome (AIDS): differentiation betweeninfectious and non-infectious diseases usinghigh-resolution CT findings. Clin Radiol. 76:50-59. 2021.

3. Kunihiro Y, Tanaka N, Kawano R, Matsumoto T, Kobayashi T,Yujiri T, Kubo M, Gondo T, Ito K. Differentiation of pulmonary complications with extensive ground-glass attenuation on high-resolution CT in immunocompromised patients. Jpn J Radiol. 39:868-876. 2021.

2020年

1. Nishiwaki K, Sugimoto KJ, Tamaki S, Hisatake J, Yokoyama H, Igarashi T, Shinagawa A, Sugawara T, Hara S, Fujikawa K, Shimizu S,Yujiri T, Tojo A, Wakita H. Optimal treatment strategy with nilotinib for patients with newly diagnosed chronic-phase chronic myeloid leukemia based on early achievement of deep molecular response (MR4.5 ): The phase 2, multicenter N-Road study. Cancer Med. 9:3742-3751.2020.

2.Imaizumi Y, Iwanaga M, Nosaka K, Ishitsuka K, Ishizawa K, Ito S, Amano M, Ishida T, Uike N, Utsunomiya A, Ohshima K, Tanaka J, Tokura Y, Tobinai K, Watanabe T, Uchimaru K, Tsukasaki K; for collaborative Investigators. Prognosis of patients with adult T-cell leukemia/lymphoma in Japan: A nationwide hospital-based study. Cancer Sci. 111:4567-4580. 2020

2019年

1. Sunami K, Matsumoto M, Fuchida SI, Omoto E, Takamatsu H, Adachi Y, Choi I, Fujishima N, Kiguchi T, Miyamoto T, Maeda A, Suzumiya J, Yamamura R, Nagafuji K, Nakazato T, Kuroda Y,Yujiri T, Takamatsu Y, Harada M, Akashi K. Bortezomib-based strategy with autologous stem cell transplantation for newly diagnosed multiple myeloma: a phase II study by the Japan Study Group for Cell Therapy and Transplantation (JSCT-MM12)Int J Clin Oncol. 24:966-975.2019

2. Takahashi T, Suzuki T, Hiroshige S, Nouno S, Matsumura T, Tominaga T,Yujiri T, Katano H, Sato Y, Hasegawa H. Transient Appearance of Plasmablasts in the Peripheral Blood of Japanese Patients with Severe Fever with Thrombocytopenia Syndrome.J Infect Dis.220:23-27.2019

3. Nakamura Y, Tanaka Y, Tanaka M, Yamamoto K, Matsuguma M, KajimuraY, Tokunaga Y,Yujiri T, Tanizawa Y. Significance of granulocyte colony-stimulating factor-combined high-dose cytarabine, cyclophosphamide, and total body irradiation in allogeneic hematopoietic cell transplantation for myeloid malignancies.Transplant Proceedings51:896-900. 2019

4. Akuta K, Kashiwagi H,Yujiri T, Nishiura N, Morikawa Y, Kato H, Honda S, Kanakura Y, Tomiyama Y. A unique phenotype of acquired Glanzmann thrombasthenia due to non function-blocking anti-αIIbβ3 autoantibodies.J Thromb Haemost. 1:206-219.2019

5. TERT and JAK2 polymorphisms define genetic predisposition to myeloproliferative neoplasms in Japanese patients.5. Matsuguma M,Yujiri T, Yamamoto K, Kajimura Y, Tokunaga Y, Tanaka M, Tanaka Y, Nakamura Y, Tanizawa Y. Int J Hematol110:690-698. 2019

6. Kunihiro Y, Hara A, Ikeda E, Nakada N, Murakami T, Hayashi M, Okabe K,Yujiri T, Kamei H, Tanaka N, Onoda H, Matsumoto T, Ito KA Case of Pulmonary Langerhans Cell Histiocytosis With Acute Progressive Nodular Lesions Depicted on High-Resolution Computed Tomography.J Thorac Imaging.34:W144-W146 2019

7. Nawata R, Sugiyama A, Harada K, Shinohara K,Yujiri T. Successful detection of MYD88 L265P mutation in Waldenström's macroglobulinemia complicated with myelofibrosis using highly sensitive digital PCR.Rinsho Ketsueki.60:903-909. 2019

8. Kunihiro Y, Tanaka N, Kawano R,Yujiri T, Kubo M, Ueda K, Gondo T, Kobayashi T, Matsumoto T. Differential diagnosis of pulmonary infections in immunocompromised patients using high-resolution computed tomography.Eur Radiol.29:6089-6099.2019

2018年

1. Hatta Y, Mizuta S, Matsuo K, Ohtake S, Iwanaga M, Sugiura I, Doki N, Kanamori H, Ueda Y, Yoshida C, Dobashi N, Maeda T,Yujiri T, Monma F, Ito Y, Hayakawa F, Takeuchi J, Kiyoi H, Miyazaki Y, Naoe T. Final analysis of the JALSG Ph+ALL202 study: tyrosine kinase inhibitor-combined chemotherapy for Ph+ALL.Ann Hematol.97:1535–1545. 2018

2. Kawajiri-Manako C, Sakaida E, Ohwada C, Miyamoto T, Azuma T, Taguchi J, Mori T, Hasegawa Y, Kondo T,Yujiri T, Yoshimitsu M, Imada K, Kurahashi S, Kahata K, Ichinohe T, Hirokawa M, Atsuta Y, Nakaseko C. The Efficacy and Long-Term Outcomes of Autologous Stem Cell Transplantation in POEMS Syndrome: a Nation-Wide Survey in Japan.Biol Blood Marrow Transplant24:1180-1186. 2018

3. Kawamoto K, Miyoshi H, Suzuki T, Kozai Y, Kato K, Miyahara M,Yujiri T, Oishi N, Choi I, Fujimaki K, Muta T, Kume M, Moriguchi S, Tamura S, Kato T, Tagawa H, Makiyama J, Kanisawa Y, Sasaki Y, Kurita D, Yamada K, Shimono J, Sone H, Takizawa J, Seto M, Kimura H, Ohshima K. A distinct subtype of Epstein Barr virus positive T/NK-cell lymphoproliferative disorder: Adult patients with chronic active Epstein Barr virus infection-like features.Haematologica103:1018-1028. 2018

4. Sakura T, Hayakawa F, Sugiura I, Murayama T, Imai K, Usui N, Fujisawa S, Yamauchi T,Yujiri T, Kakihana K, Ito Y, Kanamori H, Ueda Y, Miyata Y, Kurokawa M, Asou N, Ohnishi K, Ohtake S, Kobayashi Y, Matsuo K, Kiyoi H, Miyazaki Y, Naoe T for the Japan Adult Leukemia Study Group. High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG.Leukemia32:626-632. 2018

2017年

1. Nakamura Y, Matsuguma M, Tokunaga Y, Yamamoto K, Tanaka M, Tanaka Y, Yujiri T, Tanizawa Y. Successful treatment of Behçet’s disease associated with acute myeloid leukemia with myelodysplasia-related changes using azacitidine and tacrolimus before allogeneic hematopoietic stem cell transplantation. Intern Med 56:1199-1202. 2017

2. Ichimura T, Yoshida K, Okuno Y, Yujiri T, Nagai K, Nishi M, Shiraishi Y, Ueno H, Toki T, Chiba K, Tanaka H, Muramatsu H, Hara T, Kanno H, Kojima S, Miyano S, Ito E, Ogawa S, Ohga S. Diagnostic challenge of Diamond–Blackfan anemia in mothers and children by whole-exome sequencing. Int J Hematol 105:515-520. 2017

3. Nawata T, Kubo M, Okuda S, Omoto M, Yujiri T, Kanda T, Yano M. Successful treatment with intravenous cyclophosphamide for anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis associated with myelodysplastic syndrome. Scand J Rheumatol 46:496-498. 2017

2016年

1. Sugiyama A, Yujiri T, Tanaka M, Tanaka Y, Nakamura Y, Tanizawa Y. SIRT1 is downregulated during peripheral blood stem cell mobilization in healthy donors by granulocyte-colony stimulating factor. Ann Hematol. 95:1381–1382. 2016

2. Tanaka N, Kunihiro Y, Kobayashi T, Yujiri T, Kido S, Ueda K, Matsunaga N. High-resolution CT findings of idiopathic pneumonia syndrome after haematopoietic stem cell transplantation: based on the updated concept of idiopathic pneumonia syndrome by the American Thoracic Society in 2011. Clin Radiol. 71:953-9. 2016

3. Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H. Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults. Nat Genet 48:569-74. 2016

4. Itonaga H, Iwanaga M, Aoki K, Aoki J, Ishiyama K, Ishikawa T, Sakura T, Fukuda T, Najima Y, Yujiri T, Mori T, Kurokawa M, Nawa Y, Uchida N, Morishita Y, Hashimoto H, Eto T, Hirokawa M, Morishima Y, Nagamura-Inoue T, Atsuta Y, Miyazaki Y. Impacts of graft-versus-host disease on outcomes after allogeneic hematopoietic stem cell transplantation for chronic myelomonocytic leukemia: A nationwide retrospective study.Leukemia Res 41:48-55. 2016

5. Nakamura Y, Tanaka Y, Tanaka M, Sugiyama A, Yamamoto K, Tokunaga Y, Yujiri T, Tanizawa Y. Soluble interleukin-2 receptor index predicts the development of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation from unrelated donors. Int J Hematol 103:436-43. 2016

6. Nishiwaki S, Imai K, Mizuta S, Kanamori H, Ohashi K, Fukuda T, Onishi Y, Takahashi S, Uchida N, Eto T, Nakamae H, Yujiri T, Mori S, Nagamura-Inoue T, Suzuki R, Atsuta Y, Tanaka J. Impact of MRD and TKI on allogeneic hematopoietic cell transplantation for Ph+ALL: a study from the Adult ALL WG of the JSHCT. Bone Marrow Transplant 51:43-50. 2016

2015年

1. Sugiyama A, Yujiri T, Tanaka M, Tanaka Y, Nakamura Y, Tanizawa Y. Altered expression of circadian clock genes during peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor. Chronobiol Int 32: 934-41, 2015

2. Nakamura Y, Tanaka Y, Tanaka M, Sugiyama A, Tokunaga Y, Suehiro Y, Takeda K, Yujiri T, Tanizawa Y. Effect of early posttransplantation tacrolimus concentration on the development of acute graft-versus-host disease after cord blood transplantation. Journal of Hematopoietic Cell Transplantation 4: 74-81, 2015

2014年

1. Hayakawa F, Sakura T, Yujiri T, Kondo E, Fujimaki K, Sasaki O, Miyatake J, Handa H, Ueda Y, Aoyama Y, Takada S, Tanaka Y, Usui N, Miyawaki S, Suenobu S, Horibe K, Kiyoi H, Ohnishi K, Miyazaki Y, Ohtake S, Kobayashi Y, Matsuo K, Naoe T. Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group. Blood Cancer Journal 4: e252, 2014

2. Yujiri T, Nakamura Y, Oota I, Nakano K, Tanizawa Y. Acquired von Willebrand syndrome associated with monoclonal gammopathy of undetermined significance. Ann Hematol. 93:1427-1428, 2014

3. Yujiri T, Tanaka M, Taguchi A, Tanaka Y, Nakamura Y, Tanizawa Y. Reactivation of hepatitis B virus in a hepatitis B surface antigen-negative patient with acute promyelocytic leukemia treated with arsenic trioxide. Ann Hematol. 93:351-352, 2014

2013年

1. Kanamori H, Mizuta S, Kako S, Kato H, Nishiwaki S, Imai K, Shigematsu A, Nakamae H, Tanaka M, Ikegame K, Yujiri T, Fukuda T, Minagawa K, Eto T, Nagamura-Inoue T, Morishima Y, Suzuki R, Sakamaki H, Tanaka J Reduced-intensity allogeneic stem cell transplantation for patients aged 50 years or older with B-cell ALL in remission: a retrospective study by the Adult ALL Working Group of the Japan Society for Hematopoietic Cell Transplantation. Bone Marrow Transplant. 48:1513-1518, 2013

2. Nakamura Y, Mitani N, Ishii A, Hayashi S, Yujiri T, Ikeda E, Tanizawa Y. Idiopathic pneumonia syndrome with thrombotic microangiopathy-related changes after allogeneic hematopoietic stem cell transplantation. Int J Hematol 98:496-498, 2013

3. Nakasone H, Kanda J, Yano S, Atsuta Y, Ago H, Fukuda T, Kakihana K, Adachi T, Yujiri T, Taniguchi S, Taguchi J, Morishima Y, Nagamura T, Sakamaki H, Mori T, Murata M; GVHD Working Group of the Japan Society for Hematopoietic Cell Transplantation. A case-control study of bronchiolitis obliterans syndrome following allogeneic hematopoietic stem cell transplantation. Transpl Int. 26:631-639, 2013

4. Tanaka M, Yujiri T, Ito S, Okayama N, Takahashi T, Shinohara K, Azuno Y, Nawata R, Hinoda Y, Tanizawa Y. JAK2 46/1 haplotype is associated with JAK2 V617F-positive myeloproliferative neoplasms in Japanese patients. Int J Hematol 97:409–413, 2013

2012年

1. Mizuta S, Matsuo K, Maeda T, Yujiri T, Hatta Y, Kimura Y, Ueda Y, Kanamori H, Usui N, Akiyama H, Takada S, Yokota A, Takatsuka Y, Tamaki S, Imai K, Moriuchi Y, Miyazaki Y, Ohtake S, Ohnishi K, Naoe T. Prognostic factors influencing clinical outcome of allogeneic hematopoietic stem cell transplantation following imatinib-based therapy in BCR–ABL-positive ALL. Blood Cancer Journal 2, e72, 2012.

2. Tanaka M, Yujiri T, Tanaka Y, Mitani N, Tanimura A, Tanizawa Y. Alteration of Dickkopf-1 and receptor activator of nuclear factor-kB ligand during peripheral blood stem cell mobilization in healthy donors by granulocyte colony stimulating factor. Bone Marrow Transplant 47, 1143-1144, 2012.

2011年

1. Tanimura A, Yujiri T, Tanaka Y, Tanaka M, Mitani N, Nakamura Y, Ariyoshi K, Tanizawa Y. Activation of the unfolded protein response in primary acute myeloid leukemia cells. Int J Hematol 94, 300-302, 2011

2. Tanaka N, Kunihiro Y, Yujiri T, Ando T, Gondo T, Kido S, Matsunaga N. High-resolution computed tomography of chest complications in patients treated with hematopoietic stem cell transplantation. Jpn J Radiol. 29:229-235. 2011

3. Iida M, Fukuda T, Ikegame K, Yoshihara S, Ogawa H, Taniguchi S, Takami A, Abe Y, Hino M, Etou T, Ueda Y, Yujiri T, Matsui T, Okamura A, Tanaka J, Atsuta Y, Kodera Y, Suzuki R. Use of mycophenolate mofetil for patients received allogeneic hematopoietic stem cell transplantation in Japan. Int J Hematol 93,523-531,2011

4. Suga K, Kawakami Y, Matsunaga N, Yujiri T, Nakazora T, Ariyoshi K. F-18 FDG PET/CT findings of a case of sacral nerve root neurolymphomatosis that occurred during chemotherapy. Clin Nucl Med. 36:73-76, 2011

5. Kunihiro Y, Tanaka N, Ando T, Yujiri T, Matsunaga N. Engraftment Syndrome After Hematopoietic Stem Cell Transplantation: High-resolution Computed Tomography Findings in 2 Patients. J Thorac Imaging 26:W23-25,2011

6. Mitani N, Yujiri T, Tanaka Y, Tanaka M, Fujii Y, Hinoda Y, Tanizawa Y. Hematopoietic progenitor cell count, but not immature platelet fraction value, predicts successful harvest of autologous peripheral blood stem cells. J Clin Apheresis 26:105-110,2011

7. Miyazaki K, Yamaguchi M, Suzuki R, Kobayashi Y, Maeshima AM, Niitsu N, Ennishi D, Tamaru J-i, Ishizawa K, Kashimura M, Kagami Y, Sunami K, Yamane H, Nishikori M, Kosugi H, Yujiri T, Hyo R, Katayama N, Kinoshita T, Nakamura S. CD5-positive diffuse large B-cell lymphoma: A retrospective study in 337 patients treated by chemotherapy with or without rituximab. Ann Oncol 22:1601-1607,2011

8. Mizuta S, Matsuo K, Yagasaki F, Yujiri T, Hatta Y, Kimura Y, Ueda Y, Kanamori H, Usui N, Akiyama H,  Miyazaki Y, Ohtake S, Atsuta Y, Sakamaki H, Kawa K, Morishima Y, Ohnishi K, Naoe T,Ohno R. Pre-transplant imatinib-based therapy improves the outcome of allogeneic hematopoietic stem cell transplantation for BCR-ABL-positive acute lymphoblastic leukemia. Leukemia 25, 41-47, 2011

9. Yujiri T, Tanaka Y, Tanaka M, Takahashi T, Tanizawa Y. Alteration in serum B cell-activating factor levels in patients with idiopathic thrombocytopenic purpura after Helicobacter pylori eradication therapy. Brit J Haematol. 152, 496-498, 2011

2010年

1. Asakura M, Ikegame K, Yoshihara S, Taniguchi S, Mori T, Etoh T, Takami A, Yoshida T, Fukuda T, Hatanaka K, Kanamori H,Yujiri T, Atsuta Y, Sakamaki H, Suzuki R, Ogawa H. Use of foscarnet for cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation from a related donor. Int J Hematol 92, 351-359, 2010

2. Yujiri T, Tagami K, Tanaka Y, Mitani N, Nakamura Y, Ariyoshi K, Ando T, Tanizawa Y. Increased serum levels of high-mobility group box 1 protein in patients who developed acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. Eur J Haematol. 85, 366-367, 2010

3. Ando T, Mitani N, Yamashita K, Takahashi T, Ohama E, Miyata H,Yujiri T, Tanizawa Y. Cytomegalovirus ventriculoencephalitis in a reduced-intensity conditioning cord blood transplant recipient. Transpl Infect Dis 12,441-445, 2010

4. Ando T, Mitani N, Matsunaga K, Nakazora T, Gondo T, Yujiri T, Tanizawa Y. Gemtuzumab ozogamicin therapy for isolated extramedullary AML relapse after allogeneic hematopoietic stem-cell transplantation. Tohoku J Exp Med 220,121-126, 2010

2009年以前

Tanaka Y, Yujiri T, Tanaka M, Mitani N, Tanimura A, Tanizawa Y. Alteration of adipokines during peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor. J Clin Apheresis 24, 205-208, 2009

Yujiri T, Tanaka Y, Tanaka M, Tanizawa Y. Fluctuations in thrombopoietin, immature platelet fraction, and glycocalicin levels in a patient with cyclic thrombocytopenia. Int J Hematol 90, 429-430, 2009

Ando T, Mitani N, Matsui K, Yamashita K, Nomiyama J, Tsuru M, Yujiri T, Tanizawa Y. Recurrent extramedullary relapse of acute myelogenous leukemia after allogeneic hematopoietic stem cell transplantation in a patient with chromosomal abnormality t(8;21) and CD56 positivity. Int J Hematol 90, 374-377, 2009

Tagami K, Yujiri T, Takahashi T, Kizuki N, Tanaka Y , Mitani N, Nakamura Y, Ariyoshi K, Ando T, Gondo T, Tanizawa Y. Increased serum levels of matrix metalloproteinase-9 in acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. Int J Hematol 90, 248-252, 2009

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J. TRAF6 Establishes Innate Immune Responses by Activating NF-κB and IRF7 upon Sensing Cytosolic Viral RNA and DNA. PLoS ONE 4, e5674, 2009

Tanimura A, Yujiri T, Tanaka Y, Hatanaka M, Mitani N, Nakamura Y, Mori K, Tanizawa Y. The Anti-apoptotic Role of the Unfolded Protein Response in Bcr-Abl-positive Leukemia Cells. Leukemia Res. 33, 924-928, 2009

Yujiri T, Miyazaki M, Imoto S. A novel t(11;14)(q23;q32) in a patient with myelodysplastic syndrome. Cancer Genet Cytogenet, 188, 124-125, 2009

Yanada M, Sugiura I, Takeuchi J, Akiyama H, Maruta A, Ueda Y, Usui N, Yagasaki F, Yujiri T, Takeuchi M, Nishii K, Kimura Y, Miyawaki S, Narimatsu H, Miyazaki Y, Ohtake S, Jinnai I, Matsuo K, Naoe T, Ohno R. Prospective monitoring of BCR-ABL transcript levels in patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia undergoing imatinib-combined chemotherapy.Brit J Haematol. 143, 503-510, 2008

Ando T, Yujiri T, Nomiyama J, Mitani N, Seguchi M, Matsubara A, Tanizawa Y. Allogeneic peripheral blood stem cell transplantation from related donors mismatched at 2 HLA loci in the host-versus-graft direction. Tohoku J Exp Med 214, 159-163, 2008

Yujiri T, Tagami T, Tanimura A, Tanizawa Y. Alteration of adrenergic signals during peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor. Leukemia Res 32, 195-197, 2008

Nakamura Y, Tanaka Y, Ando T, Sato Y, Yujiri T, Tanizawa Y. Successful engraftment of the second reduced-intensity conditioning cord blood transplantation (CBT) for a patient who developed graft rejection and infectious complications after the first CBT for AML. Bone Marrow Transplant 40, 395-396, 2007

Nakamura Y, Yujiri T, Ando T, Hisano S, Tanizawa Y. Nephrotic syndrome associated with thrombotic microangiopathy following allogeneic stem cell transplantation for myelodysplastic syndrome. Brit J Haematol 136, 857-858, 2007

Tagami K*, Yujiri T*, Tanimura A, Mitani N, Nakamura Y, Ariyoshi K, Ando T, Fujii Y, Tanizawa Y. Elevation of serum high-mobility group box 1 protein during granulocyte colony stimulating factor-induced peripheral blood stem cell mobilization. Brit J Haematol 135,567-569, 2006 (*These authors contributed equally to this work)

Nakamura Y, Yujiri T, Tanizawa Y. Role of MEK kinase 1 in Bcr-Abl-Induced Self-Renewal Activity of Embryonic Stem Cells. Bull Yamaguchi Med Sch53,1-4, 2006

Yujiri T, Katsuki K, Miyazaki M, Ando T, Tsuru M, Nomiyama J, Tanizawa Y. A Case of Hand-Mirror Cell Variant of Multiple Myeloma. Int J Hematol 83, 373-374, 2006

Ando T, Yujiri T, Mitani N, Takeuchi H, Nomiyama J, Suguchi M, Matsubara A, Tanizawa Y. Donor cell-derived acute myeloid leukemia after unrelated umbilical cord blood transplantation. Leukemia 20, 744-745,2006

Nakamura Y, Yujiri T, Nawata R, Tagami K, Tanizawa Y. MEK kinase 1 is Essential for Bcr-Abl Induced STAT3 and Self-Renewal Activity in Embryonic Stem Cells. Oncogene 24, 7592-7598, 2005

Ueda K, Kawano J, Takeda K, Yujiri T, Tanabe K, Anno T, Akiyama M, Nozaki J, Yoshinaga T, Koizumi A, Shinoda K, Oka Y, Tanizawa Y. Endoplasmic Reticulum Stress Induces Wfs1 Gene Expression in Pancreatic-cells via Transcriptional Activation. Eur J Endocrinol 153, 167-176, 2005

Li Y, Minamino T, Tsukamoto O, Yujiri T, Shintani Y, Okada K, Nagamachi Y, Fujita M, Hirata A, Sanada S, Asanuma H, Takashima S, Hori M, Johnson GL, Kitakaze M. Ablation of MEKK1 Suppresses Intimal Hyperplasia by Impairing Smooth Muscle Cell Migration and uPA Expression in a Mouse Blood Flow Cessation Model. Circulation 111, 1672-1678, 2005

Ando T, Yujiri T, Tominaga T, Shinya S, Takahashi T, Nomiyama J, Seguchi M, Matsubara A, Fujii Y, Tanizawa Y. Autografting followed by a reduced-intensity conditioning unrelated donor cord blood transplantation for a patient with refractory multiple myeloma: successful engraftment with minimal toxicity. Eur J Haematol 74, 175-179, 2005

Yujiri T, Sato Y, Tanizawa Y. Sustained cytogenetic remission induced by imatinib mesylate in a chronic myeloid leukemia patient who had relapsed into lymphoid crisis after allogeneic hematopoietic stem cell transplantation. Int J Hematol 80, 67-69, 2004

Takahashi T, Yujiri T, Tanizawa Y. Helicobacter pylori and chronic ITP: the discrepancy in the clinical responses to eradication therapy might be due to differences in the bacterial strains. Blood 104, 594, 2004

Takahashi T, Yujiri T, Shinohara K, Inoue Y, Sato Y, Fujii Y, Okubo M, Zaitsu Y, Ariyoshi K, Nakamura Y, Nawata R, Oka Y, Shirai M, Tanizawa Y. Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori-associated chronic idiopathic thrombocytopenic purpura. Brit J Haematol 124, 91-96, 2004

Nawata R., Yujiri T., Nakamura Y., Ariyoshi K., Takahashi T., Sato Y., Oka Y., Tanizawa Y. MEK Kinase 1 mediates the anti-apoptotic effect of the Bcr-Abl oncogene through NF-kB activation. Oncogene 22,7774-7780, 2003

Cuevas BD, Abell AN, Witowsky JA, Yujiri T, Johnson NL, Kesavan K, Ware M, Jones PL, Weed SA, DeBiasi RL, Oka Y, Tyler, Johnson GL. MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts. EMBO J. 22, 3346-3355, 2003

Yujiri, T., Nawata, R., Takahashi, T., Sato, Y., Tanizawa, Y., Kitamura, T., Oka, Y. MEK kinase 1 interacts with focal adhesion kinase and regulates insulin receptor substrate-1 expression. J. Biol. Chem. 278, 3846-3851, 2003

Minamino T, Yujiri T, Terada N, Taffet GE, Michael LH, Johnson GL, Schneider MD. MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. Proc Natl Acad Sci U S A. 99, 3866–3871,2002

Yujiri,T., Ware M., Oyer R., Russell D., Zaitsu Y., Clarke P., Tyler K., Oka Y., Henson P., Johnson GL. Cell migration and c-Jun NH2-terminal kinase but not NFkB are regulated by MEK Kinase 1. Proc Natl Acad Sci U S A. 97, 7272-7277, 2000

Garrington T., Ishizuka T., Papst P.J., Chayama K., Webb S., Yujiri T., Sun W., Sather S., Russell D.M., Gibson S.B., Keller G., Gelfand E.W., Johnson G.L. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells. EMBO J. 19, 5387-5395, 2000

Minamino T, Yujiri T, Papst PJ, Chan ED, Johnson GL, Terada N. MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocyte. Proc Natl Acad Sci U S A. 96, 15127-32, 1999

Yujiri, T., Fanger, G.R., Garrington, T.P., Schlesinger, T. K., Gibson, S., Johnson, G.L. MEK kinase 1 transduces JNK activation in response to changes in microtubule cytoskeleton. J. Biol. Chem. 274,12605-10. 1999

Yujiri, T., Sather, S., Fanger, G. R., and Johnson, G. L. Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption. Science 282, 1911-4. 1998

Schlesinger, T. K., Fanger, G. R.,Yujiri, T., Johnson, G. L. The TAO of MEKK. Front Biosci Nov 15;3:D1181-6. 1998

Jarpe, M. B., Widmann, C., Knall, C., Schlesinger, T. K., Gibson, S., Yujiri, T., Fanger, G. R., Gelfand, E. W., and Johnson, G. L. Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death. Oncogene 17, 1475-82. 1998

Kamei S, Shinohara K, Yujiri T, Shigemoto K, Oeda E, Yohena H.Automatic isolation of bone marrow mononuclear cells using Fenwal CS-3000 Plus blood cell separator. Bull Yamaguchi Med Sch 39: 31-35. 1992

Shinohara K, Yujiri T, Kamei S, Ayame H, Tanaka M, Ando S, Tajiri M,and Kurimoto F. Increased production of GM-CSF, IL-3, IL-6 by the stimulated peripheral blood mononuclear cells in patients with aplastic anemia. Jpn Arch Int Med 39: 183-189. 1992

Shinohara K, Yujiri T, Kamei S, Ayame H, Tanaka M, Ando S, and Tajiri M.Absence of point mutation of N-ras oncogene in bone marrow cells with aplastic anemia. Int J Cell Cloning 10: 94-98. 1992

Yujiri T, Shinohara K, and Kurimoto K. Fluctuations in serum cytokine levels in the patient with cyclic neutropenia. Am J Hematol. 39:144-145.1992

特 許

特開2016-077221 :BCR−ABL阻害剤耐性関連変異の検出方法及びこれを用いたBCR−ABL阻害剤耐性を予測するためのデータ取得方法
大場 光芳, 阿部 健一, 山野 博文, 湯尻 俊昭

WO2019-004334:骨髄増殖性腫瘍に関連する遺伝子変異評価用キット
高光 恵美、大場 光芳、森弘 惇一、山野 博文, 松隈 雅史、湯尻 俊昭

WO2019-004335:遺伝子変異評価方法、遺伝子変異評価用キット
高光 恵美, 大場 光芳, 森弘 惇一, 山野 博文, 松隈 雅史, 湯尻 俊昭