コンテンツへスキップ

Publications

  • 2023年
  • 2022年
  • 2021年
  • 2020年以前
  • 受賞歴
  • Patents
  1. Herpud1 modulates hypertrophic signals independently of calmodulin nuclear translocation in rat myocardium-derived H9C2 cells

    2. Riko Fujioka, Takeshi Yamamoto, Akihiro Maruta, Yoshihide Nakamura, Naoomi Tominaga, Masako Inamitsu, Tetsuro Oda, Shigeki Kobayashi, Masafumi Yano

    Biochemical and Biophysical Research Communications. doi: 10.1016/j.bbrc.2023.02.038. PMID: 36812708

  1. 4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations

    2. Kana Tominaga♰, Naoomi Tominaga♰, Eric O Williams, Laura Rufibach, Verena Schöwel, Simone Spuler, Mohan Viswanathan, Leonard P Guarente
    ♰These authors contributed equally

    iScience. doi: 10.1016/j.isci.2021.103667. PMID: 35028538

  2. Herpud1 suppress angiotensin II induced hypertrophy in cardiomyocytes

    3. Masafumi Yano Mei Mikawa, Chihiro Sakai, Takeshi Yamamoto, Yoshihide Nakamura, Shinji Tanaka, Naoomi Tominaga, Masako Inamitsu, Tetsuro Oda, Shigeki Kobayashi

    Biochemistry and biophysics reports.. doi: 10.1016/j.bbrep.2022.101248. PMID: 35313646

  3. Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice

    4. Chihiro Sakai, Mei Mikawa, Takeshi Yamamoto, Tomoyuki Uchida, Yoshihide Nakamura, Hideaki Akase, Takeshi Suetomi, Naoomi Tominaga, Masako Inamitsu, Tetsuro Oda, Takayuki Okamura, Shigeki Kobayashi, Masafumi Yano

    Biochemical and biophysical research communications.. doi: 10.1016/j.bbrc.2022.07.038. PMID: 35872542

  1. Altered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake

    2. Nao Nishida-Aoki, Naoomi Tominaga, Nobuyoshi Kosaka, Takahiro Ochiya

    Journal of extracellular vesicles. doi: 10.1080/20013078.2020.1713527. PMID: 32082512

  2. Contribution of Extracellular Vesicles to Cancer Initiation through Cellular Senescence during Aging

    3. N Tominaga

    Cancer Studies.

  3. Indispensable roles of glycosylated extracellular vesicles for cancer cell metastasis

    4. Nobuyoshi Kosaka, Nao Nishida-Aoki, Naoomi Tominaga, Yusuke Yoshioka, Takahiro Ochiya

    CANCER SCIENCE.

  4. Disruption of circulating extracellular vesicles as a novel therapeutic strategy against cancer metastasis

    5. Nao Nishida-Aoki, Naoomi Tominaga, Fumitaka Takeshita, Hikaru Sonoda, Yusuke Yoshioka, Takahiro Ochiya

    Molecular Therapy. doi: 10.1016/j.ymthe.2016.10.009. PMID: 28129113

  5. A novel platform for cancer therapy using extracellular vesicles

    6. Naoomi Tominaga, Yusuke Yoshioka, Takahiro Ochiya

    Advanced Drug Delivery Reviews. doi: 10.1016/j.addr.2015.10.002. PMID: 26482189

  6. Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

    7. Nature communications. doi: 10.1038/ncomms7716. PMID: 25828099

  7. Micromanaging of tumor metastasis by extracellular vesicles

    8. Seminars in Cell & Developmental Biology. doi: 10.1016/j.semcdb.2015.02.016. PMID: 25746922

  8. RPN2-mediated glycosylation of tetraspanin CD63 regulates breast cancer cell malignancy

    9. Naoomi Tominaga, Keitaro Hagiwara, Nobuyoshi Kosaka, Kimi Honma, Hitoshi Nakagama, Takahiro Ochiya

    Molecular cancer. doi: 10.1186/1476-4598-13-134. PMID: 24884960

  9. Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells

    10. Makiko Ono, Nobuyoshi Kosaka, Naoomi Tominaga, Yusuke Yoshioka, Fumitaka Takeshita, Ryou-u Takahashi, Masayuki Yoshida, Hitoshi Tsuda, Kenji Tamura, Takahiro Ochiya

    Science signaling. doi: 10.1126/scisignal.2005231. PMID: 24985346

  10. Dark side of the exosome: the role of the exosome in cancer metastasis and targeting the exosome as a strategy for cancer therapy

    11. Nobuyoshi Kosaka, Yusuke Yoshioka, Naoomi Tominaga, Keitaro Hagiwara, Takeshi Katsuda, Takahiro Ochiya

    Future Oncology. doi: 10.2217/fon.13.222. PMID: 24754596

  11. Trash or Treasure: extracellular microRNAs and cell-to-cell communication

    12. Nobuyoshi Kosaka, Yoshioka Yusuke, Keitaro Hagiwara, Naoomi Tominaga, Takeshi Katsuda, Takahiro Ochiya

    Frontiers in genetics. doi: 10.3389/fgene.2013.00173. PMID: 24046777

  12. Functional analysis of exosomal microRNA in cell–cell communication research

    13. Nobuyoshi Kosaka, Yusuke Yoshioka, Keitaro Hagiwara, Naoomi Tominaga, Takahiro Ochiya

    Circulating MicroRNAs. doi: 10.1007/978-1-62703-453-1_1. PMID: 23719938

  13. Clinicopathological analysis of GATA3-positive breast cancers with special reference to response to neoadjuvant chemotherapy

    14. N Tominaga, Y Naoi, K Shimazu, T Nakayama, N Maruyama, A Shimomura, SJ Kim, Y Tamaki, S Noguchi

    Annals of oncology. doi: 10.1093/annonc/mds120. PMID: 22767585

  14. 70-Gene classifier for differentiation between paclitaxel-and docetaxel-sensitive breast cancers

    15. Y Naoi, T Tanei, K Kishi, R Tsunashima, N Tominaga, Y Baba, T Nakayama, K Shimazu, SJ Kim, Y Tamaki, S Noguchi

    Cancer letters. doi: 10.1016/j.canlet.2011.09.032. PMID: 22018777

  15. Prediction of pathologic complete response to sequential paclitaxel and 5‐fluorouracil/epirubicin/cyclophosphamide therapy using a 70‐gene classifier for breast cancers

    16. Yasuto Naoi, Kazuki Kishi, Tomonori Tanei, Ryo Tsunashima, Naoomi Tominaga, Yosuke Baba, Seung Jin Kim, Tetsuya Taguchi, Yasuhiro Tamaki, Shinzaburo Noguchi

    Cancer. doi: 10.1002/cncr.25953. PMID: 21305539

  16. Development of 95-gene classifier as a powerful predictor of recurrences in node-negative and ER-positive breast cancer patients

    17. Yasuto Naoi, Kazuki Kishi, Tomonori Tanei, Ryo Tsunashima, Naoomi Tominaga, Yosuke Baba, Seung Jin Kim, Tetsuya Taguchi, Yasuhiro Tamaki, Shinzaburo Noguchi

    Breast cancer research and treatment. doi: 10.1007/s10549-010-1145-z. PMID: 20803240

  17. High genomic grade index associated with poor prognosis for lymph node‐negative and estrogen receptor‐positive breast cancers and with good response to chemotherapy

    18. Yasuto Naoi, Kazuki Kishi, Tomonori Tanei, Ryo Tsunashima, Naoomi Tominaga, Yosuke Baba, Seung Jin Kim, Tetsuya Taguchi, Yasuhiro Tamaki, Shinzaburo Noguchi

    Cancer. doi: 10.1002/cncr.25626. PMID: 20878674

  1. 革新的研究の発掘と育成（FOCS）プロジェクト研究奨励賞受賞

    2. 2023年度FOCSプロジェクト研究奨励賞を受賞いたしました。

  1. Method for suppressing brain metastasis

    2. Takahiro Ochiya, Naoomi Tominaga
    US Patent App. 16/745,967

  2. Method for diagnosing and treating cancer brain metastasis and drug delivery system for enabling passage through blood-brain barrier

    3. Takahiro Ochiya, Naoomi Tominaga
    US Patent 10,544,466

  3. Compositions and methods for treating dysferlinopathy

    4. Leonard P. Guarente, Kana TOMINAGA, Naoomi TOMINAGA, Mohan VISWANATHAN, Eric WILLAMS
    WO2023278684A1

©2021 TOMINAGA LABORATORY. All Rights Reserved.

Neve | Powered by WordPress