2025.05.22
Small nuclear ribonucleoprotein autoantibody associated with blood-nerve barrier breakdown in Guillain-Barré syndrome
A research group led by Associate Professor Fumitaka Shimizu of the Department of Clinical Neurology, Graduate School of Medicine (Medical Sciences), Yamaguchi University; Professor Michiaki Koga of the Department of Clinical Nursing Science, Graduate School of Medicine (Health Sciences); Professor Yoichi Mizukami of the Resource Development Division (Genetic Experiment Facility), Integrated Science Experimental Center; and Assistant Professor Kenji Watanabe has discovered snRNP antibodies, novel autoantibodies that disrupt the blood-nerve barrier in Guillain-Barré syndrome.
- Division of Advanced Cell Therapy
- Yukio Takeshita（Department of Neurotherapeutics）
- Division of Advanced Genome Editing Therapy
- Masayuki Nakamori（Neurology）
- Paper Title：Small nuclear ribonucleoprotein autoantibody associated with blood-nerve barrier breakdown in Guillain-Barré syndrome
- Author：Fumitaka Shimizu, Michiaki Koga, Yoichi Mizukami, Kenji Watanabe, Ryota Sato, Yukio Takeshita, Toshihiko Maeda, Takashi Kanda, Masayuki Nakamori
- Publication：Neurology Neuroimmunology & Neuroinflammation
- Posted on: May 19, 2025
- D O I：https://doi.org/10.1212/NXI.0000000000200405
＜Research Inquiries＞
Department of Neurotherapeutics Graduate School of Medicine, Yamaguchi University
Fumitaka Shimizu
TEL: 0836-22-2719
E-mail: fshimizu@yamaguchi-u.ac.jp
Researcher Information: https://researchmap.jp/7000022012
＜Public Relations＞
Yamaguchi University The Research Institute for Cell Design and Medical Science (Life Science Support Section, Academic Research Division)
Tel: 0836-85-3065
E-mail: sh088@yamaguchi-u.ac.jp